RNA biology of bacterial pathogens
All microorganisms, including pathogens, must cope with dramatic environmental changes. Bacterial adaption to stress is a multifaceted process demanding precise control of gene expression at all layers of regulation. While
we have learned a great deal of bacterial physiology from regulation by transcriptional control elements over last decades, the role of post-transcriptional regulators has only more recently been appreciated. In my laboratory, we study the regulatory principles and physiological roles of regulatory RNAs in bacterial pathogens, including Vibrio cholerae.